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Miller RA, Chu Q, Xie J, Foretz M, Viollet B, Birnbaum MJ (2013) Biguanides suppress hepatic glucagon signalling by decreasing production of cyclic AMP

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215 High expression of NO is a characteristic of UC, and inhibition of the NF-B pathway can also inhibit the expression of IL-6 and iNOS, thereby reducing the content of NO and protecting the intestinal mucosa

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