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PTH enhances CYP27B1 expression via activation of the adenylyl cyclaseprotein kinase A (ACPKA) signaling pathway, thereby promoting the synthesis of active vitamin D (12)

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15 Although many research studies and clinical laboratories define vitamin B 12 deficiency at a level of less than 150 pg per mL (110.67 pmol per L), or in some cases 200 pg per mL, patients with values above these levels may be symptomatic and benefit from treatment