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95 % CI (-095, 117), P = 0839) (online Supplementary Fig

Both have a place, but they are not interchangeable, and neither is a substitute for addressing an underlying medical cause when one exists

& Carnevale, E

At high concentrations of ROS, lipids, especially PUFAs, are oxidatively damaged, causing lipid peroxidation and inducing ferroptosis

The addition of GSH or expression of Grxs 1 and 2 significantly improves mutant SOD1 solubility in cell culture, whereas reducing the levels of intracellular GSH decreases SOD1 solubility, suggesting that GSH reduction promotes the aggregation of mutant SOD1 (Guareschi et al., 2012)

Fundamentals of redox regulation in biology