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Lancet 377: 526, 2011 [DOI] [PubMed] [Google Scholar] 32.OBrien LM, Hooper M, Flemmer M, Marik PE: Chronic acetaminophen ingestion resulting in severe anion gap metabolic acidosis secondary to 5-oxoproline accumulation: An under diagnosed phenomenon

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[3] Nikolaeva et al

Important Note on the Evidence Base Important note on the evidence base: The preclinical AOD-9604 literature in obese mouse and Zucker rat models is consistent and reproducible