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As the new obesity pharmacotherapies will lead up to 1525% mean WL, intensive lifestyle interventions may provide small additional WL benefit to these treatments [11, 106]

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This process also contributes to the removal of damaged organelles, such as mitochondria and ER, and misfolded or aggregate-prone proteins (Mizushima, 2011)

After reconstitution, keep refrigerated at 28C and avoid repeated freeze-thaw cycles