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SGLT2 inhibitors enhance fatty acid oxidation and ketogenesis, potentially reducing renal accumulation of long-chain acylcarnitines [172], while metformin attenuates the acute eGFR decline induced by SGLT2 inhibitors [173]

Harvey J, Wing RR, Mullen M

Thigh injections tend to absorb slightly slower than abdominal injections, which some researchers find helpful for managing initial side effects

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Subcutaneous fat is more directly measurable but less metabolically active, so peptide studies on it tend to use different endpoints than those used in visceral-fat-focused research

This could change how hormones are made and regulated