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It is characterized by a gamma-peptide bond between the carboxyl group of the glutamate side chain and cysteine (Figure 1)

The gastrointestinal tract contains proteases and peptidases specifically designed to break down peptides into individual amino acids for absorption

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Penicillamine is generally used first-line to treat symptomatic patients in the UK

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Avoid consuming them with foods or beverages that may interfere with absorption, such as dairy products or coffee