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At the end of the treatment, more patients in the pioglitazone groups achieved the primary outcome and resolution of MASH than did those in the placebo group, and pioglitazone significantly reduced the fibrosis scores

Contemp Oncol (Pozn) (2013) 17(1):15

Glutathione is one of the body's most important naturally occurring antioxidants and is found in virtually every cell

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Finally, NAC's protective effect on mitochondria [24] ensures the maintenance of cellular energy metabolism and prevents apoptosis, which is significant in conditions where mitochondrial dysfunction contributes to pain and disease progression

Although further study of these interactions is necessary, patients receiving these agents concurrently should be monitored for the desired therapeutic response to vitamin B12