I would like to revisit the subject now in this article
VenugopalanVKGopakumarLRKumaranAKChatterjeeNSSomanVPeeralilSet al
The treatment gained popularity rapidly through social media and word of mouth
Similarly, in mesangial cells, GLP-1 receptor agonists have been shown to suppress either high-glucose-induced or AGEs-induced pro-fibrotic signalling pathways, including NF-B activation and TGF-1 expression, leading to reduced ECM deposition [60,61], and to suppress their proliferation via AMPK activation [62]
Its also possible that rapid A1c reductions from semaglutide were responsible those with very steep A1c drops in the first fifteen weeks of the trial were, in fact, more likely to experience retinopathy
Front Endocrinol (2021) 12:741764