This technique has the benefit of a relatively simple, gradual, and structured titration, which may improve confidence with and acceptance of an increasing need for multiple daily injections and may also reduce the incidence of hypoglycemia compared with going straight to basalbolus therapy [20]
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et al, Hyperhomocysteinemia in myelodysplastic syndromes: specific association with autoimmunity and cardiovascular disease
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Zouboulis CC, Desai N, Emtestam L, Hunger RE, Ioannides D, Juhsz I, et al