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These drugs have 4060% response rates when used as monotherapies, with many of those responses lasting a long time [209]

doi: 10.3390/ph17081081

[DOI] [PMC free article] [PubMed] [Google Scholar] 19.S

Researchers have yet to examine strategies to preserve or increase muscle mass during weight loss induced by GLP-1 drugs

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40,41 In contrast, in tumors such as neuroblastoma or small cell lung cancer, which are characterized by high genetic instability and poor differentiation, clonal evolution driven by stochastic genetic mutations may play a more dominant role than hierarchical stemness