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475 Deletion of the ZIP2 gene notably intensified myocardial I/R injury, whereas upregulation of ZIP2 demonstrated the potential to mitigate I/R injury

Obesity or Overweight With Weight-Related Conditions While not all GLP-1 medications are FDA-approved specifically for weight loss, some like Wegovy ( semaglutide ) are, and others including Mounjaro have shown substantial weight reduction benefits

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A prespecified interim histologic assessment was performed at week 72 among the first 800 randomized participants

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