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Compared with DPP-4i users, GLP-1 RA users were younger (mean age 56.1 vs 62.3 years), had a higher body mass index (36.5 vs 32.1 kg/m), and were less likely to be male (45.2% vs 50.4%)

Key interactions include: Central nervous system depressants: Combining baclofen with alcohol, sedatives, or opioids can increase drowsiness and dizziness

However, it is recommended to consult with a healthcare professional to determine the appropriate dosage and ensure compatibility with any medications or health conditions

PT-141 addresses this by working at the brain level, stimulating the desire pathways that blood-flow medications don't reach