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Acetaminophen Gastric decontamination with activated charcoal should be administered just prior to N-acetylcysteine (NAC) to decrease systemic absorption if acetaminophen ingestion is known or suspected to have occurred within a few hours of presentation

Pasternak T, Palme K, Paponov IA (2020) Glutathione enhances Auxin Sensitivity in Arabidopsis roots

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The manufacturers positioning as a natural alternative is doing regulatory work as much as marketing work: because the formulation doesnt contain deoxycholic acid or another recognised active pharmaceutical ingredient, it has consistently been classified as a cosmetic product rather than a medicine in the UK

One potential concern is the dose