Recommended Dosing Collagen: Most studies suggest a range of 10g to 20g per day for noticeable benefits in skin and joint health
The loss of periplasmic CuZnSOD causes loss of virulence and might be an attractive target for new antibiotics
This therapy utilizes a small molecule known as 5-Amino-1MQ, which targets an enzyme called Nicotinamide N-methyltransferase (NNMT)
Ding F, Ma B, Nazary-Vannani A, et al
Glutathione supplementation supports thyroid health by reducing the need for selenium and providing the thyroid cells with an oxidative stress regulation tool they natively use.* Glutathione helps to recycle glutathione peroxidase, removing the toxic products the enzyme captures.* This means the thyroid cells will not need to produce extra glutathione peroxidase to cope with oxidative stress.* Additionally, glutathione neutralizes ROS directly, independent of the antioxidant-enabling activity it performs for glutathione peroxidase.* Using a glutathione supplement can thus modify the threat model of thyroid issues from selenium insufficiency or excess oxidative stress.* Rather than an individual with compromised thyroid function worrying about both impaired hormone production and thyroid damage, they would only need to be mindful of maintaining a minimum viable level of oxidative stress to provide for essential functions (although it is highly unlikely to fully deprive thyroid cells of the baseline level of oxidative stress they need to produce hormones)
While it shares structural similarities with GHK-CU, the single amino acid difference produces notably different biological effects
