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Common short-term side effects may include: Temporary water retention or bloating Mild joint stiffness or tingling Flushed skin or warmth at injection site Slight headache or fatigue (especially when beginning use) Peptide secretagogues like Ipamorelin appear to exhibit fewer adverse effects than GH or GHRH analogs and are highly selective for the GH axis (Smith et al., Journal of Endocrinological Investigation )

Weight-loss drugs can harm a developing baby, and it is not known if tirzepatide passes into breast milk

Case report: Development of vanishing bile duct syndrome in Stevens-Johnson syndrome complicated by hemophagocytic lymphohistiocytosis

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