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In tendon explant and fibroblast systems, it is linked to focal adhesion signaling and cell migration behavior

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Despite the accumulating evidence around pathways engaged by the GLP-1R and other GPCRs in target tissues, there is still substantial uncertainty about the precise molecular mechanisms involved, particularly with regards to the spatiotemporal organisation of their signalling and their presence in spatially restricted subcellular (or even suborganelle) signalling hubs or nanodomains 61