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However, generally excreted does not mean entirely without consequence. Emerging research has raised questions about whether chronically elevated serum B12 levels may serve as a marker for underlying conditions or could be associated with certain health concerns

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Detoxification: Unlike cyanocobalamin, which contains a cyanide molecule that must be detoxified and excreted by the body, Methylcobalamin does not pose this additional burden on the detoxification systems

No evidence-based guidelines regarding the use of B 12 testing in people with suspected B 12 deficiency