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The pocket surface of mTYR is more deeply embedded within the protein, positioning the dual copper-binding site at the pocket surface

GHK-Cu (Glycyl-L-Histidyl-L-Lysine-copper, 402 Da) is a tripeptide-copper complex naturally present in human plasma

Altered AC levels in peripheral tissues may indicate systemic metabolic dysregulation affecting energy homeostasis and immune-metabolic pathways in depression [13]