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& Schulze, J

Users are happy with how fast they see progress

The liver responds to GH by producing IGF-1 , and IGF-1 is what actually drives the downstream tissue effects clinicians associate with growth hormone protein synthesis, satellite-cell activation for muscle repair, lipolysis, collagen synthesis, and bone remodeling

"Unlike plaques, oxidative stress is difficult to see down a microscope, so the theory has always been at a disadvantage psychologically in terms of popularity in the field

However, the translation from rodent research to human outcomes is not guaranteed, and no large randomized controlled trials in humans have been published