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As recently reviewed, OCTN2 is overexpressed in endometrial, ovarian, renal, pancreatic cancers and also in glioblastoma (GBM) even if neurons do not normally use fatty acids to derive energy (Juraszek and Nalecz, 2019)

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Environ Pollut 304:e119237

While most intracellular glutathione is in a reduced state (GSH) with approximately 1% as an oxidized form (GSSG), this proportion can decrease in response to a variety of cellular stressors, including heavy metals, high glucose concentrations, poor nutrition, heat shock, reactive oxygen and nitrogen species, cigarette smoke, and other toxins including persistent organic pollutants