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In a Phase I clinical trial, a PYY analog named Y14 peptide was administered subcutaneously every 7 to 14 days

doi: 10.1016/j.toxicon.2003.11.013 41 Flores-DazM.Alape-GirnA.ClarkG.CatimelB.HirabayashiY.NiceE.et al

Nrf2, a member of the capncollar family of basic regionleucine zipper transcription factors involved in transcription of antioxidant genes in response to xenobiotic stress, is also a critical regulator of cellular oxidative stress in sepsis (Kolls, 2006) and a regulator of exacerbated proinflammatory cytokine release (cytokine storm) and loss of T lymphocytes (leukopenia) that characterize the most aggressive presentation of SARS-CoV-2-mediated COVID-19 infection (Kobayashi et al., 2016

Morales-Rosales SL, Rivero-Segura NA and Knigsberg M (2020) Mitochondrial function in aging

Research indicates that antioxidants like vitamin E can prevent lipid peroxidation and iron accumulation in neurodegenerative conditions associated with brain iron accumulation (NBIA), partially improving the physiological pathology of affected cells (Surez-Carrillo et al., 2023)

Heliyon 9 (3), e14006