On the physical side, you might notice constant tiredness that doesn't improve with rest, heavy legs during workouts, shortness of breath on efforts that shouldn't wind you, pale skin, and a need for frequent napping
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Animal studies show systemic effects at lower absolute doses via injection
The recommendation: remove the vial from refrigeration 15-20 minutes before drawing the dose, or warm the filled syringe in your palm for 60 seconds before injecting
It is supplied in single-dose configurations because once exposed to air, the absence of preservative means bacterial growth can begin
It does not change insulin levels