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MTHFR deficiency has also been associated with neurologic and psychiatric disease

Second, GLP-1s seemed almost grotesquely ambitious within a biopharma industry that had evolved away from mass market drugs and towards advanced modalities for niche, genetically-determined oncology and rare disease indications

Today, GLP-1 drugs give millions of people new hope in their weight-loss journey, helping them achieve healthier lives and better long-term outcomes

PMCID: PMC8504390

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Overall, the study found that using GLP-1 drugs likely prevented about seven cases of substance use disorder and 12 incidents involving serious harm for every 1,000 users over three years, Al-Aly said