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Pushing through severe side effects for months is counterproductive if it leads to inconsistent adherence or early discontinuation

Epub 2019 Nov 27

Hair loss is not listed as a top adverse effect of GLP-1 receptor agonists, but both clinical trials and real-world experiences suggest it does occur in a minority of users

This drug is contraindicated in patients with personal/family history of MTC or in patients with multiple endocrine neoplasia syndrome type 2

Retatrutide is an investigational triple receptor agonist (GLP-1, GIP, and glucagon) currently in clinical trials for obesity and type 2 diabetes

Participants in clinical trials who maintained protein intake above 90g daily and performed regular resistance training lost 65 lbs of fat while losing only 3 lbs of muscle on average