12, 13 There does not appear to be any link between PUVA lentigines and development of melanoma
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Microbial dysbiosischaracterized by diminished microbial diversity and altered community compositionhas been implicated in the disruption of epidermal differentiation signals, modulation of immune function, activation of proinflammatory pathways, and compromise of skin barrier integrity through microbe-derived metabolites [93]
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Figure 10 5.4 Protective effects on pulmonary disease via multifaceted mechanisms Respiratory infectious diseases remain a significant global challenge, as demonstrated by the COVID-19 pandemic, which was caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and annual influenza outbreaks (114)
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