The only comparison that settles this kind of question is a head-to-head trial, in which both molecules are given to the same population under the same protocol
We show readers that GLP-1RAs have also been found to significantly reduce the risks of heart failure, atherosclerosis (AS), and hypertension, highlighting their broad therapeutic potential
Plus, GLP-1 is involved in stress response and the HPA axis.[ref] The brain stem controls a lot of our basic, involuntary functions, such as heart rate and breathing
Here is the full UK research guide
There were 27 MACE-3 (cardiovascular death, heart attack, or stroke) events in the retatrutide cohort and 23 in the placebo arm
Switch to the thigh if nausea is a problem