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GLP-1 receptors have been identified as expressed on certain tumour cell populations particularly in hormone-sensitive malignancies including endometrial, ovarian, and some breast cancers, as well as meningiomas

Nevertheless, confirmation in human T2DM versus obesity cohorts requires dedicated adipose tissue studies

Modifies costimulatory molecules to lower inflammation (Inhibits MHCII, CD80, CD86, CD275) [ 21 ]

for instance, diabetes mellitus elevates oxidative stress and iron dysregulation, potentially exacerbating ferroptosis in diabetic hearts and accelerating cardiomyopathy

Health plans and providers can leverage these findings to offer more effective, accessible, and comprehensive weight management options

2025;8(10):e2540890