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The enzyme protein disulfide isomerase (PDI) catalyzes this reaction by accepting electrons from thiol residues in the polypeptide chain substrate, leading to its oxidation

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It may be one of the first peptides shown to act as a selective gene expression modulator, without the off-target chaos of pharmacological epigenetic drugs

CYP2E1 and oxidative liver injury by alcohol

Glutamate and GABA Energy Metabolism in Depression Positron emission tomography (PET) (160, 161) and 13 C-MRS are widely used techniques for evaluating brain energy metabolism (162) in humans and rodents