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( 10.1093/advances/nmy057) [DOI] [PMC free article] [PubMed] [Google Scholar] Schisterman EF, Sjaarda LA, Clemons T, Carrell DT, Perkins NJ, Johnstone E, Lamb D, Chaney K, Van Voorhis BJ, Ryan Get al

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Nitrous oxide, a commonly used anesthetic, oxidizes and inactivates vitamin B 12 , thus inhibiting both of the vitamin B 12 -dependent enzymes, and can produce many of the clinical features of vitamin B 12 deficiency, such as megaloblastic anemia and neuropathy

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Women interested in PT-141 therapy should receive a full medical evaluation to determine if it is appropriate for their condition

The 1 mg arm of Phase 2 produced direct measurement