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There may be implications for liver, kidney, or thyroid function in some individuals

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Last Published 12.01.2025 Effective Date: 12.01.2025 This policy addresses the use of Izervay (avacincaptad pegol) and Syfovre (pegcetacoplan injection) for the treatment of geographic atrophy (GA) secondary to age-related macular degeneration (AMD)

The cell viability was assessed by Hoechst staining of the nucleus (see Methods) and hence assessment of total cell numbers after 72 h of treatment, which is a good proxy for cell survival and cell growth upon prolonged compound exposure

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