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The low sample size and lack of long-term follow-up of patients can be reported as the limitations of this study

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A major source of ROS during reperfusion is from the mitochondria, as a result of mitochondrial dysfunction

The former is often seen early in treatment and the latter usually after 1-2 years of treatment

GLP-1 medications also carry an FDA black box warning for risk of thyroid C-cell tumors, and should not be used by patients with a personal or family history of medullary thyroid cancer or multiple endocrine neoplasia type 2 (MEN2)

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