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These medications are administered via subcutaneous injection and are typically prescribed as part of a comprehensive weight management program that includes diet, exercise, and behavioral changes

Therefore, IR is a new effective target for systemic PD treatment, especially in the brain (30)

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Amgen has previously claimed that this mechanism not only triggers weight loss but also helps patients keep the pounds off after stopping treatment

Endocrinology 154 , 49394945 (2013)