B12 is indispensable for a healthy immune system due to its involvement in critical functions
However, the cause of this decrease is yet to be determined
This makes it a useful system for studying receptor-driven endocrine responses
McKean MA, Haydu LE, Ma J, Jr BR, Hwu WJ, Patel, SP, Diab A, Glitza IC, Tawbi HAH, Wong MK, McQuade JL, Hwu P, Davies MA , Amaria RN
a d , Flow cytometry plots showing the gating strategies used to identify human melanoma cells in the blood ( a ) or lymph ( b ) of NSG mice or mouse melanoma cells in the blood ( c ) or lymph ( d ) of C57BL mice
It did not affect T cell uptake due to compensatory upregulation of the glutamine transporter SLC6A14 in CD8 + T cells, which increased CD8 + T cell activation and glutathione synthesis (Jin et al., 2020)