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doi: 10.15252/embj.2020106230 70 RaneJ

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Chemical modification of metformin into sulfenamides and sulfonamides has also improved the cellular accumulation of these compounds in cancer cells, with a subsequent increase in their cytotoxic efficacy

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Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas , 49 (12), e5826