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Conclusions We discussed in the present article about the importance of the anti-inflammatory properties and the beneficial metabolic and cardio-renal effects of GLP1-RAs, together with their safety

REDEFINE is an ongoing phase 3 trial acting as market evaluation for both CagriSema and cagrilintide, with 60% randomised to CagriSema, 10% cagrilintide, 10% semaglutide, and 20% placebo, where minimum age at inclusion was 55 years with no upper limit [117]

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