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(4) Potential mechanisms may involve reduction of NF-B and MAP kinase signaling, and interactions with vasodilators like nitric oxide (NO), thereby possibly lowering pro-inflammatory cytokine output

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MAIN COMPOUND PATENTS The active ingredient, semaglutide, as used in Novo Nordisks products Ozempic, Rybelsus and Wegovy is protected by two key compound patents, U.S

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However, researchers acknowledge that the drugs efficiency could be hampered by its limited reach