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179 Ass-deficient prostate and pancreatic cancers have also been shown to be sensitive to ADI-PEG20, and ADI-PEG20 promotes cell death by inducing autophagy and apoptosis

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It is indicated for conditions such as pyridoxine deficiency from poor diet or malabsorption, anemia due to low B, and certain cases of neonatal seizures that respond to vitamin B therapy

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