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These tests can give you and your doctor a more complete picture of how the medication is affecting your body and help catch potential issues early

We also analysed whether persistent GLP-1RA users experienced fewer cardiovascular outcomes and lower all-cause mortality than non-persistent patients

Tirzepatide activates two hormone receptors simultaneously: GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide)

Early-phase and preclinical data suggest that glucagon receptor activation may increase energy expenditure and promote hepatic fat reduction, though the clinical significance of these effects in humans is still being evaluated

J Clin Endocrinol Metab 81(11):40594067

et al.) 314 (Springer, 2010)