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In the Corpas sermorelin trial, no serious adverse events were reported over 6 months [1]

Dose is the amount of drug given via each method of administration

From a biochemical standpoint, pushing the balance too far toward NADH relative to NAD plus can disrupt redox balance, which helps explain why overly aggressive dosing or stacking multiple NAD approaches may increase side effects rather than benefits

doi: 10.3389/fimmu.2025.1578940 Received 18 February 2025 Accepted 24 March 2025 Published 10 April 2025 Volume 16 - 2025 Edited by Fabrizio Fontana, University of Milan, Italy Reviewed by Bjrn Steen Sklhegg, University of Oslo, Norway Josephine Anthony, Meenakshi Academy of Higher Education and Research, India Updates Copyright 2025 Fang, Gao, Jiang, Li and Li

Choi YB, Lipton SA (2000)

Substantial weight and BMI reductions with lipoic acid supplementation in overweight or obese subjects were also reported in a prior meta-analysis (106)