GLP-1 agonists are primary pharmacologic interventions with far stronger evidence for independent weight reduction
As a fixed-dose combination, CagriSema was assessed in two phase 3 studies (REDEFINE 1 and 2), resulting in significant and clinically relevant reductions in body weight compared with placebo in adults with overweight or obesity, with [8] or without type 2 diabetes [9]
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PMID 10469335
References (1) Francis GL, et al
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