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Key Mechanistic Differences# The mechanistic distinction is significant: Dihexa promotes structural synaptic plasticity through growth factor signaling (building new connections), while PE-22-28 modulates functional neuronal properties through ion channel blockade (changing how existing neurons fire)

Cys 2 ) or cystine-free/GSH-supplemented (750 M) medium for 48 h, and the relative abundance of indicated intracellular (e-g) and extracellular (f-g) metabolites was determined

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NAD + metabolism: pathophysiologic mechanisms and therapeutic potential

BPC-157 supplied by NewBioRx is intended strictly for laboratory research use and is not approved for human or veterinary applications

Cold Spring Harbor Press