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The following paragraphs summarize the characteristics of the 13 forms of paediatric PFIC described so far

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(General reference on nasal bioavailability and molecular weight thresholds.) Merkus FW, Verhoef JC, Schipper NG, Marttin E

A diet high in iron leads to reduced GSH levels and increased lipid peroxidation, causing significant heart damage and the development of hypertrophic cardiomyopathy

It is for this reason that the expression of GPx1 and GPx3 is highly reactive to the deficiency in Se

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