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Reducing that from 365 injections a year to ~52 could help with compliance

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Additionally, dietary protein-derived metabolites, including tryptophan-indole, as well as LPS from Gram-negative bacteria, directly promote the production of GLP-1 (66, 67)

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[12] Metformin: Anchor in the GLP-1 RA Care Continuum Journey The mechanistic, real-world, clinical trials and pharmacovigilance evidence landscape suggests metformin as the potential anchor pharmacological agent across the entire GLP-1 RA care continuum, during therapy and beyond.Table 1 summarises the key potential outcome benefits at each phase