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While most studies demonstrate improvement in weight or BMI on treatment (114122), trials of longer duration that may need to be combined with co-interventions are needed to address its long-term effects on body mass and metabolic health
Generally, at the beginning of MASLD development, the expression/activity of antioxidant enzymes usually increases to protect organisms against the increased production of reactive oxygen species
Can hormonal imbalance cause histamine intolerance
This gradual timeline is expected because treatment begins at a lower dose to reduce side effects, and it takes several weeks for the medication to reach a steady state
Disadvantages are: not FDA-approved for women, reversibly raising liver tests (need to monitor every 3 months)
The stimulatory effects of specific formulations can exacerbate these conditions, making a medical evaluation essential before initiating treatment
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