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The Alzheimer's disease clinical spectrum

Individuals with certain health conditions, such as Lebers disease (a rare inherited eye disease), should avoid B12 supplements as it can worsen the condition

Additional information Journal peer review information: Nature Communications thanks the anonymous reviewers for their contribution to the peer review of this work

It presents with a broad clinical spectrum, ranging from asymptomatic or non-specific symptoms, such as fatigue or lightheadedness, to severe manifestations, including nausea, vomiting, alteration of consciousness, and even coma, which can be life-threatening 3,4

A novel dodecadepsipeptide, cereulide, isolated from Bacillus cereus causes vacuole formation in HEp-2 cells