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Puberty is delayed in male growth hormone receptor gene-disrupted mice

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Free Radicals, Antioxidants and Functional Foods: Impact on Human Health

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Beyond cancer biology, DES(1-3) IGF-1 has been investigated in neuroprotection models, where its high potency and reduced IGFBP binding facilitate clean receptor activation in brain tissue preparations where IGFBP concentrations would otherwise limit native IGF-1 activity