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This effect, mediated by inactivation of the phosphoinositide 3-kinase activation (PI3K/AKT) and extracellular-signal-regulated kinase (ERK) signaling pathways, offers an insight into the complex mechanisms of miscarriage and preeclampsia during Se deficiency

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The overexpression of HIF-1 reflects the presence of hypoxic conditions and oxidative stress in the affected tissue

Found naturally in muscle tissue, the brain, and the heart, L-carnosine is a protein-building block that helps maintain cellular health and support the bodys antioxidant defenses [4]