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Our findings are consistent with those of the cited reports

In obese murine models, GLP-1 receptor activation has been demonstrated to reduce macrophage infiltration into adipose tissue and to suppress inflammatory signaling (Nuclear factor-B (NF-B), jun N-terminal kinase (JNK)) in both adipocytes and adipose tissue macrophages (ATM), changes that were associated with improved insulin sensitivity [12]

The comparison between WT and DB group showed that 621 upregulated and 589 downregulated genes (Fig

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