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Key extracted elements included, study title, condition, intervention, primary outcome measures locations and enrolment as shown in Table 2

Concurrent dosing reduces efficacy by creating NAD+ demand spikes and competitive receptor saturationtiming separation is the critical variable for synergy

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doi:10.1155/2012/736837 Vakov J, Koan L, Vako L, Perjsi P

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that is, cholesterol is converted to bile acids in the liver, 95% bile acids are absorbed by the distal ileum and returned to the liver, and 5% bile acids are excreted in the stool